Posted by Admin on March, 28, 2023
3-Hydroxyacetophenone, also known as 3-HAP, is a chemical compound with the molecular formula C8H8O2. It is an organic compound supplied by a 3-Hydroxyacetophenone Supplier that belongs to the class of aromatic ketones. The chemical structure of 3-HAP consists of a benzene ring with a ketone group (-CO-) and a hydroxyl group (-OH) attached at positions 1 and 3, respectively.
Synthesis Of 3-Hydroxyacetophenone
The synthesis of 3-Hydroxyacetophenone can be achieved through various methods. It includes the reaction of 3-bromophenol with acetone or the condensation of 3-phenylpropanaldehyde with acetic acid. It can also be obtained through the oxidation of 3-acetyl phenol with hydrogen peroxide. The reduction of 3-nitro acetophenone with sodium borohydride.
What is Hydroxyacetophenone?
Hydroxyacetophenone, also known as HAP, is an organic compound with the molecular formula C8H8O2. It is a derivative of acetophenone, with a hydroxyl group (-OH) attached at position 1. Hydroxyacetophenone is used in the synthesis of various pharmaceuticals, perfumes, and flavours.
It is also studied for its potential biological activities, including antioxidant, anti-inflammatory, and anti-cancer properties. Its structural similarity to curcumin, a natural compound with potent anti-cancer properties. It has led researchers to investigate its potential as a curcumin analogue.
Hydroxyacetophenone is a versatile compound with the potential for further research and development in various fields.
Applications Of 3-Hydroxyacetophenone
3-Hydroxyacetophenone supplied by a 3-Hydroxyacetophenone Supplier finds its use in various industrial applications. It includes the production of pharmaceuticals, perfumes, and flavours. It is an essential intermediate in the synthesis of pharmaceuticals such as antihistamines, antimicrobials, and antifungal agents.
Flavouring Agent In Food Products
The compound is also used as a flavouring agent in food products. It provides a sweet, floral, and fruity scent to the products. Furthermore, it is employed in the production of cosmetics, soaps, and detergents due to its pleasing scent and antimicrobial properties.
Apart from its industrial applications, 3-Hydroxyacetophenone has been studied for its potential biological activities. It exhibits antioxidant, anti-inflammatory, and anti-cancer properties. Studies have shown that 3-HAP can scavenge free radicals and inhibit lipid peroxidation, indicating its potential as an antioxidant agent.
It has also been found to reduce inflammation by inhibiting the production of inflammatory mediators.
Moreover, 3-Hydroxyacetophenone Suppliers has shown promising anti-cancer activity in various cancer cell lines. It induces apoptosis (programmed cell death) in cancer cells by activating the caspase cascade. A series of molecular events leads to the death of cells.
It also inhibits the growth and proliferation of cancer cells by downregulating the expression of oncogenes.
3-HAP has been found to possess selective toxicity towards cancer cells, leaving normal cells unharmed. This makes it a promising candidate for the development of anti-cancer drugs with minimal side effects.
Furthermore, its structural similarity to curcumin, a natural compound with potent anti-cancer properties. It has prompted researchers to investigate its potential as a curcumin analogue.
3-Hydroxyacetophenone is a versatile compound with a wide range of industrial applications and potential biological activities. Its antioxidant and anti-cancer properties make it a promising candidate for the development of drugs and therapies for various diseases.
Further research is needed to fully elucidate its biological activities and to explore its potential as a therapeutic agent.
This entry was posted on March, 28, 2023 at 16 : 03 pm and is filed under Acetophenone Derivatives. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response from your own site.
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